Reduced Bacteria and Bioburden
A critical benefit of MIST Therapy when treating nonhealing wounds is its ability to reduce the amount of bacteria within and below the wound bed. Bacterial cells are more rigid and susceptible to micromechanical stress. When treated with MIST Therapy, many bacterial membranes will fracture and the cell will die.
MIST Therapy has been shown to reduce a wide range of bacteria, including MRSA, VRE and pseudomonas. (21)
A prospective, multi-center single arm study used biopsies to demonstrate the amount of bacteria within the wound bed and MIST Therapy’s impact on the bacterial count after two weeks of treatment (6 sessions).
- Eleven (11) patients with Stage 3 pressure ulcers from three wound care centers were enrolled
- Each participant received a biopsy at enrollment and after two weeks of 3x/wk MIST treatments
- All participants needed to have greater than >105 bacterial count, show no signs of infection and be free-from antibiotics to be included in the study. (23)
Of the 12 types of bacteria seen on initial evaluation, all but one showed a significant reduction. Overall mean bacterial burden was reduced 50% from 4 x 107 to 2 x 107 after 2 weeks of MIST Therapy treatments.
50% Reduction in Bacteria